Clarity LC Columns
Purification and characterization of synthetic oligonucleotides
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Purification and characterization of synthetic oligonucleotides
Separate N-1 failure sequences from target oligo with >90% purities. Trityl-off purification of DNA, RNA, thioates and modified/labeled oligonucleotides. Preparative dimensions and particle sizes for loads >5 umol. Purify oligos up to 60 mer in length.
Available Phases
| Clarity Oligo-RP | Designed for reversed phase purification of oligonucleotides with balanced hydrophobicity and polar selectivity, based on composite particle TWIN technology. Easily separates N-1 failure sequences from the target oligo with >90% purities; trityl-off purification of DNA, RNA, thioates and modified/labeled oligos. |
| Clarity Oligo-XT | Unlike traditional fully porous oligo columns, Clarity Oligo-XT uses core-shell technology to provide extremely high efficiencies at both low and high oligo concentrations, suited to the LC-MS/MS analysis demanded by TK and PK/PD studies of oligo therapeutics. |
| Clarity Oligo-MS | Phenomenex page did not return its own content when scraped - needs a manual check. |
Manufacturer information: Clarity HPLC/PREP Columns
Specifications
| Separation technique | Reversed Phase (RP) |
|---|---|
| Application | Biological Analysis |
| Pore size | 100 Å |
| Particle size | 1.7 µm, 2.6 µm, 3 µm, 5 µm, 10 µm |
| Phases available | 3 |
| Catalogue codes | 57 |
Specifications for Clarity LC Columns
| Column Phase | Oligo-MS or Oligo-RP or Oligo-XT |
| Column Particle Size | 3 or 5 or 10 or 1.7 or 2.6 |
| Column Length | 30 or 50 or 100 or 150 or 250 or N/A |
| Column Internal Diameter | 2 or 10 or 30 or 50 or 2.1 or 4.6 or 21.2 or N/A |
| Column Format | Bulk Media or Analytical or Preparative (AXIA Packed) |
| Column Option | Standard or AXIA Packed |
| Column Pore Size | 100 |
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